Biology:Ribitol-5-phosphate 2-dehydrogenase
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ribitol-5-phosphate 2-dehydrogenase | |||||||||
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Identifiers | |||||||||
EC number | 1.1.1.137 | ||||||||
CAS number | 37250-67-2 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a ribitol-5-phosphate 2-dehydrogenase (EC 1.1.1.137) is an enzyme that catalyzes the chemical reaction
- D-ribitol 5-phosphate + NAD(P)+ [math]\displaystyle{ \rightleftharpoons }[/math] D-ribulose 5-phosphate + NAD(P)H + H+
The 3 substrates of this enzyme are D-ribitol 5-phosphate, NAD+, and NADP+, whereas its 4 products are D-ribulose 5-phosphate, NADH, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-ribitol-5-phosphate:NAD(P)+ 2-oxidoreductase. This enzyme is also called dehydrogenase, ribitol 5-phosphate. This enzyme participates in pentose and glucuronate interconversions.
References
- "Ribitol-5-phosphate dehydrogenase from Lactobacillus plantarum". Biochimica et Biophysica Acta 67: 525–30. April 1963. doi:10.1016/0006-3002(63)91863-8. PMID 13948358.
Original source: https://en.wikipedia.org/wiki/Ribitol-5-phosphate 2-dehydrogenase.
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