Biology:4-(hydroxymethyl)benzenesulfonate dehydrogenase
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Short description: Class of enzymes
| 4-(hydroxymethyl)benzene-sulfonate dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.257 | ||||||||
| CAS number | 167973-64-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a 4-(hydroxymethyl)benzenesulfonate dehydrogenase (EC 1.1.1.257) is an enzyme that catalyzes the chemical reaction
- 4-(hydroxymethyl)benzenesulfonate + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] 4-formylbenzenesulfonate + NADH + H+
Thus, the two substrates of this enzyme are 4-(hydroxymethyl)benzenesulfonate and NAD+, whereas its 3 products are 4-formylbenzenesulfonate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-(hydroxymethyl)benzenesulfonate:NAD+ oxidoreductase. This enzyme participates in 2,4-dichlorobenzoate degradation.
References
- "Degradative pathways for p-toluenecarboxylate and p-toluenesulfonate and their multicomponent oxygenases in Comamonas testosteroni strains PSB-4 and T-2". Microbiology 142 ( Pt 9) (9): 2419–27. September 1996. doi:10.1099/00221287-142-9-2419. PMID 8828208.
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