Medicine:List of adverse effects of sertraline

Short description: Wikipedia list article

Adverse effects of sertraline by incidence.

Very common (>10%)

• Fatigue
• Insomnia
• Nausea
• Dry mouth
• Diarrhea
• Headache
• Ejaculation disorder
• Dizziness
• Sweating or Excessive Sweating

Common (1-10%)

• Agitation
• Anorexia
• Constipation
• Dyspepsia (indigestion)
• Decreased libido
• Sweating
• Tremor
• Vomiting
• Impaired concentration
• Nervousness
• Paroniria (i.e., depraved or morbid dreaming/nightmares)
• Yawning
• Palpitations
• Increased sweating
• Hot flushes
• Weight decrease
• Weight increase
• Myoclonus
• Hypertonia
• Bruxism (teeth grinding)
• Hypoaesthesia
• Menstrual irregularities
• Sexual dysfunction
• Rash
• Vision abnormal
• Asthenia
• Chest pain
• Paraesthesia
• Tinnitus (hearing ringing in the ears)
• Birth defects (if taken during pregnancy), this include:

 Heart Defects,
 Cleft Lip,
 Cleft Palate, 
 Clubbed Feet,
 Omphalocele 
 Hydrocephalus and any other birth defects.

Uncommon (0.1-1%)

• Hypertension (high blood pressure)
• Hyperkinesia
• Bronchospasm
• Oesophagitis (swollen oesophagus)
• Dysphagia
• Haemorrhoids
• Purpura
• Cold Sweat
• Dry skin
• Nocturia
• Urinary Retention
• Polyuria (excessive urination)
• Vaginal Haemorrhage
• Malaise
• Chills
• Pyrexia (fever)
• Thirst
• Pollakiuria
• Micturition disorder
• Salivary Hypersecretion
• Tongue Disorder
• Osteoarthritis
• Muscular Weakness
• Back Pain
• Muscle Twitching
• Eructation (belching)
• Dyspnoea (air hunger)
• Epistaxis (nose bleed)
• Edema peripheral
• Periorbital Edema
• Syncope
• Postural dizziness
• Tachycardia (high heart rate)
• Urticaria (hives)
• Migraine
• Abnormal bleeding (esp. in the GI tract)
• Muscle cramps
• Arthralgia
• Depressive symptoms
• Euphoria
• Hallucination
• Alopecia (hair loss)
• Urinary Retention (being unable to pass urine)
• Pruritus
• Amnesia memory loss.
• Urinary incontinence
• Eye pain
• Asymptomatic elevations in serum transaminases
• Abnormal semen
• Melaena (black faeces due to a bleed in the stomach)
• Coffee ground vomiting
• Haematochezia
• Stomatitis (swollen mouth)
• Tongue ulceration
• Tooth Disorder
• Glossitis (soreness/swelling of the tongue)
• Mouth Ulceration
• Laryngospasm
• Hyperventilation (breathing more often than required to keep one's blood sufficiently oxygenated)
• Hypoventilation (breathing less often than required to keep one's blood sufficiently oxygenated)
• Stridor
• Dysphonia (voice disorder)
• Upper Respiratory Tract Infection
• Rhinitis (irritation/inflammation inside the nose)
• Hiccups
• Apathy
• Thinking Abnormal

Rare (<0.1%)

• Allergic reaction
• Allergy
• Anaphylactoid reaction
• Face oedema
• Priapism
• facial hyperpigmentation
• Atrial arrhythmia
• AV block
• Coma
• Peripheral Ischaemia
• Injury
• Vasodilation Procedure
• Lymphadenopathy
• Involuntary muscle contractions
• Galactorrhoea (lactation that is unrelated to pregnancy or breastfeeding)
• Gynaecomastia (swelling of breast tissue in men)
• Hyperprolactinaemia (high blood prolactin levels)
• Hypothyroidism (underactive thyroid gland)
• Syndrome of inappropriate secretion of antidiuretic hormone (SIADH)
• Pancreatitis (swollen pancreas)
• Altered platelet function
• Haematuria (blood in the urine)
• Leukopenia (low white blood cell count)
• Thrombocytopenia (low blood platelet count)
• Increased coagulation times
• Abnormal clinical laboratory results
• Hyponatraemia (low blood sodium)
• Conversion Disorder
• Drug Dependence
• Paranoia
• Myocardial Infarction (heart attack)
• Bradycardia
• Cardiac Disorder
• Suicidal Ideation/behaviour
• Sleep Walking
• Premature Ejaculation
• Hyperglycemia (high blood sugar)
• Hypoglycemia (low blood sugar)
• Hypercholesterolaemia (high blood cholesterol)
• Vasculitis
• Aggressive reaction
• Psychosis (hallucinations and delusions)
• Mania (a dangerously elated mood)
• Menorrhagia (an abnormally excessive amount of menstrual bleeding)
• Atrophic Vulvovaginitis
• Balanoposthitis
• Genital Discharge
• Angioedema
• Photosensitivity skin reaction
• Enuresis
• Visual field defect
• Abnormal liver function
• Dermatitis
• Dermatitis Bullous
• Rash Follicular
• Glaucoma
• Lacrimal Disorder
• Scotoma
• Diplopia
• Photophobia
• Hyphaema
• Mydriasis
• Hair Texture Abnormal
• Neoplasm
• Diverticulitis
• Choreoathetosis
• Dyskinesia
• Hyperaesthesia
• Sensory Disturbance
• Gastroenteritis
• Otitis Media
• Skin Odour Abnormal

Unknown frequency

• QTc prolongation
• Allergic Reaction
• Allergy
• Neuroleptic malignant syndrome. A potentially fatal reaction that most often occurs as a result of the use of antipsychotic drugs. It is characterised by fever, muscle rigidity, rhabdomyolysis (muscle breakdown), profuse sweating, tachycardia, tachypnoea (rapid breathing), agitation.
• Stevens–Johnson syndrome a potentially fatal skin reaction.
• Toxic epidermal necrolysis another potentially fatal skin reaction.
• Torsades de pointes a potentially fatal change in the heart's rhythm.
• Cerebrovascular spasm
• Serotonin syndrome similar to neuroleptic malignant syndrome but develops more rapidly (over a period of hours instead of days/weeks for neuroleptic malignant syndrome)
• Bone fracture
• Movement disorders
• Diabetes mellitus
• Dyspnoea
• Jaundice yellowing of the skin, mucous membranes and eyes due to an impaired ability of the liver to clear the haem breakdown by product, bilirubin.
• Hepatitis
• Liver failure
• Persistent Sexual Dysfunction