Biology:(+)-Menthofuran synthase
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Short description: Class of enzymes
| (+)-Menthofuran synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.14.13.104 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
(+)-Menthofuran synthase (EC 1.14.13.104, menthofuran synthase, (+)-pulegone 9-hydroxylase, (+)-MFS, cytochrome P450 menthofuran synthase) is an enzyme with systematic name (+)-pulegone,NADPH:oxygen oxidoreductase (9-hydroxylating).[1][2] This enzyme catalyses the following chemical reaction
- (+)-pulegone + NADPH + H+ + O2 [math]\displaystyle{ \rightleftharpoons }[/math] (+)-menthofuran + NADP+ + H2O
Menthofuran synthase is a heme-thiolate protein (P-450).
References
- ↑ "Demonstration that menthofuran synthase of mint (Mentha) is a cytochrome P450 monooxygenase: cloning, functional expression, and characterization of the responsible gene". Archives of Biochemistry and Biophysics 390 (2): 279–86. June 2001. doi:10.1006/abbi.2001.2378. PMID 11396930.
- ↑ "Menthofuran regulates essential oil biosynthesis in peppermint by controlling a downstream monoterpene reductase". Proceedings of the National Academy of Sciences of the United States of America 100 (24): 14481–6. November 2003. doi:10.1073/pnas.2436325100. PMID 14623962. Bibcode: 2003PNAS..10014481M.
External links
- (+)-menthofuran+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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