Biology:(+)-borneol dehydrogenase

From HandWiki
Short description: Class of enzymes
(+)-borneol dehydrogenase
Identifiers
EC number1.1.1.198
CAS number67185-75-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a (+)-borneol dehydrogenase (EC 1.1.1.198) is an enzyme that increases the rate of, or catalyzes, the chemical reaction

(+)-borneol + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] (+)-camphor + NADH + H+

Thus, the two substrates of this enzyme are (+)-borneol and NAD+, whereas its 3 products are (+)-camphor, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (+)-borneol:NAD+ oxidoreductase. This enzyme is also called bicyclic monoterpenol dehydrogenase.

References

  • "Biosynthesis of monoterpenes. Partial purification and characterization of a bicyclic monoterpenol dehydrogenase from sage (Salvia officinalis)". Arch. Biochem. Biophys. 188 (1): 182–93. 1978. doi:10.1016/0003-9861(78)90371-5. PMID 677891. 
  • "Metabolism of monoterpenes: Specificity of the dehydrogenases responsible for the biosynthesis of camphor, 3-thujone, and 3-isothujone". Arch. Biochem. Biophys. 258 (1): 287–91. 1987. doi:10.1016/0003-9861(87)90346-8. PMID 3310901. 

External links