Biology:(S)-carnitine 3-dehydrogenase

From HandWiki
Short description: Class of enzymes
(S)-carnitine 3-dehydrogenase
Identifiers
EC number1.1.1.254
CAS number169277-49-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a (S)-carnitine 3-dehydrogenase (EC 1.1.1.254) is an enzyme that catalyzes the chemical reaction

(S)-carnitine + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] 3-dehydrocarnitine + NADH + H+

Thus, the two substrates of this enzyme are (S)-carnitine and NAD+, whereas its 3 products are 3-dehydrocarnitine, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S)-carnitine:NAD+ oxidoreductase.

References

  • "Purification and properties of a new enzyme, D-carnitine dehydrogenase, from Agrobacterium sp. 525a". Biosci. Biotechnol. Biochem. 61 (6): 1055–8. 1997. doi:10.1271/bbb.61.1055. PMID 9214773.