Biology:4-(Gamma-L-glutamylamino)butanoyl-(BtrI acyl-carrier protein) monooxygenase
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Short description: Class of enzymes
| 4-(gamma-L-glutamylamino)butanoyl-(BtrI acyl-carrier protein) monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.14.14.13 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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4-(gamma-L-glutamylamino)butanoyl-(BtrI acyl-carrier protein) monooxygenase (EC 1.14.14.13, btrO (gene)) is an enzyme with systematic name 4-(gamma-L-glutamylamino)butanoyl-(BtrI acyl-carrier protein),FMN:oxygen oxidoreductase (2-hydroxylating).[1] This enzyme catalyses the following chemical reaction
- 4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] + FMNH2 + O2 [math]\displaystyle{ \rightleftharpoons }[/math] 4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI acyl-carrier protein] + FMN + H2O
4-(gamma-L-glutamylamino)butanoyl-(BtrI acyl-carrier protein) monooxygenase catalyses a step in the biosynthesis of the side chain of the aminoglycoside antibiotics of the butirosin family.
References
- ↑ "Biosynthesis of the unique amino acid side chain of butirosin: possible protective-group chemistry in an acyl carrier protein-mediated pathway". Chemistry & Biology 12 (6): 665–75. June 2005. doi:10.1016/j.chembiol.2005.04.010. PMID 15975512.
External links
- 4-(gamma-L-glutamylamino)butanoyl-(BtrI+acyl-carrier+protein)+monooxygenase at the US National Library of Medicine Medical Subject Headings (MeSH)
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