Biology:Benzoyl-CoA 2,3-dioxygenase

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Benzoyl-CoA 2,3-dioxygenase
Identifiers
EC number1.14.12.21
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Benzoyl-CoA 2,3-dioxygenase (EC 1.14.12.21, benzoyl-CoA dioxygenase/reductase, BoxBA, BoxA/BoxB system) is an enzyme with systematic name benzoyl-CoA,NADPH:oxygen oxidoreductase (2,3-hydroxylating).[1][2][3] This enzyme catalyses the following chemical reaction

benzoyl-CoA + NADPH + H+ + O2 [math]\displaystyle{ \rightleftharpoons }[/math] 2,3-dihydro-2,3-dihydroxybenzoyl-CoA + NADP+

Benzoyl-CoA 2,3-dioxygenase is involved in aerobic benzoate metabolism in Azoarcus evansii.

References

  1. "New enzymes involved in aerobic benzoate metabolism in Azoarcus evansii". Molecular Microbiology 54 (1): 223–38. October 2004. doi:10.1111/j.1365-2958.2004.04263.x. PMID 15458418. 
  2. "Genes coding for a new pathway of aerobic benzoate metabolism in Azoarcus evansii". Journal of Bacteriology 184 (22): 6301–15. November 2002. doi:10.1128/jb.184.22.6301-6315.2002. PMID 12399500. 
  3. "Reinvestigation of a new type of aerobic benzoate metabolism in the proteobacterium Azoarcus evansii". Journal of Bacteriology 183 (6): 1899–908. March 2001. doi:10.1128/JB.183.6.1899-1908.2001. PMID 11222587. 

External links