Biology:Carnitine 3-dehydrogenase
From HandWiki
| carnitine 3-dehydrogenase | |||||||||
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| Identifiers | |||||||||
| EC number | 1.1.1.108 | ||||||||
| CAS number | 9045-45-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a carnitine 3-dehydrogenase (EC 1.1.1.108) is an enzyme that catalyzes the chemical reaction
- carnitine + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] 3-dehydrocarnitine + NADH + H+
Thus, the two substrates of this enzyme are carnitine and NAD+, whereas its 3 products are 3-dehydrocarnitine, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is carnitine:NAD+ 3-oxidoreductase.
References
- "Reinigung und Eigenschaften der Carnitindehydrogenase aus Pseudomonas aeruginosa" (in German). Eur. J. Biochem. 6 (2): 196–201. 1968. doi:10.1111/j.1432-1033.1968.tb00437.x. PMID 4302217.
- "Kinetische Untersuchungen zum Reaktionsmechanismus der Carnitindehydrogenase aus Pseudomonas aeruginosa" (in German). Eur. J. Biochem. 10 (1): 56–60. 1969. doi:10.1111/j.1432-1033.1969.tb00654.x. PMID 4310279.
External links
- carnitine+dehydrogenase at the US National Library of Medicine Medical Subject Headings (MeSH)
- EC 1.1.1.108
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