Biology:Costunolide synthase

From HandWiki
Short description: Class of enzymes
Costunolide synthase
Identifiers
EC number1.14.13.120
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Costunolide synthase (EC 1.14.13.120) is an enzyme with systematic name germacra-1(10),4,11(13)-trien-12-oate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating).[1] This enzyme catalyses the following chemical reaction

germacra-1(10),4,11(13)-trien-12-oate + NADPH + H+ + O2 [math]\displaystyle{ \rightleftharpoons }[/math] (+)-costunolide + NADP+ + 2 H2O

Costunolide synthase is a heme-thiolate protein (P-450).

References

External links