Biology:D-amino-acid N-acetyltransferase

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D-amino-acid N-acetyltransferase
Identifiers
EC number2.3.1.36
CAS number37257-15-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a D-amino-acid N-acetyltransferase (EC 2.3.1.36) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + a D-amino acid [math]\displaystyle{ \rightleftharpoons }[/math] CoA + an N-acetyl-D-amino acid

Thus, the two substrates of this enzyme are acetyl-CoA and D-amino acid, whereas its two products are CoA and N-acetyl-D-amino acid.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:D-amino-acid N-acetyltransferase. Other names in common use include D-amino acid acetyltransferase, and D-amino acid-alpha-N-acetyltransferase. This enzyme participates in phenylalanine metabolism.

References

  • "Reinigung und Eigenschaften von Acetyl-CoA:D-Aminosaure-alpha-N-Acetyltransferase aus Hefe". Biochem. Z. 342: 54–65. 1965.