Biology:D-arabinitol 2-dehydrogenase
From HandWiki
| D-arabinitol 2-dehydrogenase | |||||||||
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| Identifiers | |||||||||
| EC number | 1.1.1.250 | ||||||||
| CAS number | 336883-93-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a D-arabinitol 2-dehydrogenase (EC 1.1.1.250) is an enzyme that catalyzes the chemical reaction
- D-arabinitol + NAD+ ⇌ D-ribulose + NADH + H+
Thus, the two substrates of this enzyme are D-arabinitol and NAD+, whereas its 3 products are D-ribulose, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-arabinitol:NAD+ 2-oxidoreductase (D-ribulose-forming). This enzyme is also called D-arabinitol 2-dehydrogenase (ribulose-forming).
References
- "D-arabitol metabolism in Candida albicans: studies of the biosynthetic pathway and the gene that encodes NAD-dependent D-arabitol dehydrogenase". J. Bacteriol. 175 (19): 6314–20. 1993. doi:10.1128/jb.175.19.6314-6320.1993. PMID 8407803.
- "Identification, purification, and characterization of a D-arabinitol-specific dehydrogenase from Candida tropicalis". Biochem. Biophys. Res. Commun. 196 (3): 1323–9. 1993. doi:10.1006/bbrc.1993.2397. PMID 8250887.
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