Biology:Diapolycopene oxygenase

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Diapolycopene oxygenase
Identifiers
EC number1.14.99.44
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Diapolycopene oxygenase (EC 1.14.99.44, crtP) is an enzyme with systematic name 4,4'-diapolycopene,AH2:oxygen oxidoreductase (4,4'-hydroxylating).[1][2] This enzyme catalyses the following chemical reaction

4,4'-diapolycopene + 4 AH2 + 4 O2 [math]\displaystyle{ \rightleftharpoons }[/math] 4,4'-diapolycopenedial + 4 A + 6 H2O

Diapolycopene oxygenase is involved in the biosynthesis of C30 carotenoids such as staphyloxanthin.

References

  1. "Identification of a carotenoid oxygenase synthesizing acyclic xanthophylls: combinatorial biosynthesis and directed evolution". Chemistry & Biology 12 (4): 453–60. April 2005. doi:10.1016/j.chembiol.2005.02.010. PMID 15850982. 
  2. "Novel carotenoid oxidase involved in biosynthesis of 4,4'-diapolycopene dialdehyde". Applied and Environmental Microbiology 71 (6): 3294–301. June 2005. doi:10.1128/AEM.71.6.3294-3301.2005. PMID 15933032. 

External links