Biology:Erythrulose reductase
From HandWiki
| erythrulose reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.162 | ||||||||
| CAS number | 52064-49-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, an erythrulose reductase (EC 1.1.1.162) is an enzyme that catalyzes the chemical reaction
- erythritol + NADP+ [math]\displaystyle{ \rightleftharpoons }[/math] D-erythrulose + NADPH + H+
Thus, the two substrates of this enzyme are erythritol and NADP+, whereas its 3 products are D-erythrulose, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is erythritol:NADP+ oxidoreductase. This enzyme is also called D-erythrulose reductase.
References
- "Studies on D-tetrose metabolism. IV. Purification and some properties of D-erythrulose reductase from beef liver". J. Biochem. (Tokyo) 75 (2): 333–45. February 1974. PMID 4152124.
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