Biology:Interiotherin

From HandWiki

Interiotherins are lignans isolated from Kadsura.[1][2]

They have a core of dibenzocyclooctadiene and contain methyl and methoxy side chains.[3] They have a role as anti-HIV agent.[4]

References

  1. "Interiotherins C and D, two new lignans from Kadsura interior and antitumor-promoting effects of related neolignans on Epstein-Barr virus activation". Journal of Natural Products 65 (9): 1242–5. September 2002. doi:10.1021/np0105127. PMID 12350139. 
  2. "Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior". Journal of Natural Products 59 (11): 1066–8. November 1996. doi:10.1021/np9601667. PMID 8946749. Bibcode1996JNAtP..59.1066C. 
  3. Coleman, Robert S.; Gurrala, Srinivas Reddy (1 April 2005). "Asymmetric Synthesis of the Dibenzocyclooctadiene Lignans Interiotherin A and Gomisin R". Organic Letters 7 (9): 1849–1852. doi:10.1021/ol050476t. PMID 15844922. 
  4. PubChem. "Interiotherin A" (in en). https://pubchem.ncbi.nlm.nih.gov/compound/21125391.