Biology:L-arabinitol 4-dehydrogenase
From HandWiki
| L-arabinitol 4-dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 L-arabinitol 4-dehydrogenase homotetramer, Neurospora crassa | |||||||||
| Identifiers | |||||||||
| EC number | 1.1.1.12 | ||||||||
| CAS number | 9028-19-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a L-arabinitol 4-dehydrogenase (EC 1.1.1.12) is an enzyme that catalyzes the chemical reaction
- L-arabinitol + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] L-xylulose + NADH + H+
Thus, the two substrates of this enzyme are L-arabinitol and NAD+, whereas its 3 products are L-xylulose, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-arabinitol:NAD+ 4-oxidoreductase (L-xylulose-forming). Other names in common use include pentitol-DPN dehydrogenase, and L-arabitol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions.
References
- "A new pathway of pentose metabolism". Biochem. Biophys. Res. Commun. 3 (5): 554–9. 1960. doi:10.1016/0006-291X(60)90174-1. PMID 13692998.
- "L-Arabinose metabolism by cell-free extracts of Penicillium chrysogenum". Biochim. Biophys. Acta 46 (2): 271–8. 1961. doi:10.1016/0006-3002(61)90750-8. PMID 13692999.
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