Biology:Long-chain-alcohol dehydrogenase
From HandWiki
long-chain-alcohol dehydrogenase | |||||||||
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Identifiers | |||||||||
EC number | 1.1.1.192 | ||||||||
CAS number | 76774-36-2 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a long-chain-alcohol dehydrogenase (EC 1.1.1.192) is an enzyme that catalyzes the chemical reaction
- a long-chain alcohol + 2 NAD+ + H2O [math]\displaystyle{ \rightleftharpoons }[/math] a long-chain carboxylate + 2 NADH + 2 H+
The 3 substrates of this enzyme are long-chain alcohol, NAD+, and H2O, whereas its 3 products are long-chain carboxylate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is long-chain-alcohol:NAD+ oxidoreductase. Other names in common use include long-chain alcohol dehydrogenase, and fatty alcohol oxidoreductase. This enzyme participates in fatty acid metabolism.
References
- "Characterization of fatty alcohol:NAD+ oxidoreductase from rat liver". The Journal of Biological Chemistry 254 (8): 2892–6. April 1979. PMID 34610.
Original source: https://en.wikipedia.org/wiki/Long-chain-alcohol dehydrogenase.
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