Biology:MMP21

From HandWiki
Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Matrix metalloproteinase-21 (MMP-21) is an enzyme that in humans is encoded by the MMP21 gene.[1][2]

Function

This gene encodes a member of the matrix metalloproteinase family. Proteins in this family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, and disease processes, such as asthma and metastasis. The encoded protein may play an important role in embryogenesis, particularly in neuronal cells, as well as in lymphocyte development and survival.[2]

References

  1. "MMP-28, a new human matrix metalloproteinase with an unusual cysteine-switch sequence is widely expressed in tumors". Gene 265 (1–2): 87–93. Mar 2001. doi:10.1016/S0378-1119(01)00360-2. PMID 11255011. 
  2. 2.0 2.1 "Entrez Gene: MMP21 matrix metallopeptidase 21". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=118856. 

Further reading

External links

  • The MEROPS online database for peptidases and their inhibitors: M10.026