Biology:Monosaccharide-transporting ATPase
From HandWiki
Short description: Class of enzymes
| monosaccharide-transporting ATPase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.6.3.17 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a monosaccharide-transporting ATPase (EC 3.6.3.17) is an enzyme that catalyzes the chemical reaction
- ATP + H2O + monosaccharideout [math]\displaystyle{ \rightleftharpoons }[/math] ADP + phosphate + monosaccharidein
The 3 substrates of this enzyme are ATP, H2O, and monosaccharide, whereas its 3 products are ADP, phosphate, and monosaccharide.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (monosaccharide-importing). This enzyme participates in abc transporters - general.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2GX6.
References
- Higgins CF (1992). "ABC transporters: from microorganisms to man". Annu. Rev. Cell Biol. 8: 67–113. doi:10.1146/annurev.cb.08.110192.000435. PMID 1282354.
- "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases". Res. Microbiol. 146 (4): 271–8. 1995. doi:10.1016/0923-2508(96)81050-3. PMID 7569321.
- "The Agrobacterium tumefaciens virulence gene chvE is part of a putative ABC-type sugar transport operon". J. Bacteriol. 179 (7): 2452–8. 1997. doi:10.1128/jb.179.7.2452-2458.1997. PMID 9079938.
- Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol.. Advances in Microbial Physiology 40: 81–136. doi:10.1016/S0065-2911(08)60130-7. ISBN 978-0-12-027740-7. PMID 9889977.
- "Utilization of D-ribose through D-xylose transporter". FEMS Microbiol. Lett. 163 (2): 255–61. 1998. doi:10.1111/j.1574-6968.1998.tb13054.x. PMID 9673030.
- The Transporter Factsbook, Academic Press, San Diego, 1998.
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