Biology:NAT8
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
N-acetyltransferase 8 is a protein that in humans is encoded by the NAT8 gene.[1]
Clinical relevance
Mutations in the NAT8 gene have been associated with chronic kidney disease.[2]
References
- ↑ "Entrez Gene: N-acetyltransferase 8 (GCN5-related". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9027.
- ↑ "Human metabolic individuality in biomedical and pharmaceutical research". Nature 477 (7362): 54–60. September 2011. doi:10.1038/nature10354. PMID 21886157. Bibcode: 2011Natur.477...54S.
Further reading
- "Two endoplasmic reticulum (ER)/ER Golgi intermediate compartment-based lysine acetyltransferases post-translationally regulate BACE1 levels.". J. Biol. Chem. 284 (4): 2482–92. 2009. doi:10.1074/jbc.M804901200. PMID 19011241.
- "Isolation and mapping of a novel human kidney- and liver-specific gene homologous to the bacterial acetyltransferases.". J. Hum. Genet. 43 (4): 255–8. 1998. doi:10.1007/s100380050084. PMID 9852678.
- "High-throughput mapping of a dynamic signaling network in mammalian cells.". Science 307 (5715): 1621–5. 2005. doi:10.1126/science.1105776. PMID 15761153. Bibcode: 2005Sci...307.1621B.
- "Molecular identification of NAT8 as the enzyme that acetylates cysteine S-conjugates to mercapturic acids.". J. Biol. Chem. 285 (24): 18888–98. 2010. doi:10.1074/jbc.M110.110924. PMID 20392701.
- "Methamphetamine-induced neuronal protein NAT8L is the NAA biosynthetic enzyme: implications for specialized acetyl coenzyme A metabolism in the CNS.". Brain Res. 1335: 1–13. 2010. doi:10.1016/j.brainres.2010.04.008. PMID 20385109.
- "Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis.". Dev. Biol. 234 (2): 483–96. 2001. doi:10.1006/dbio.2001.0261. PMID 11397015.
- "N-acetyltransferase 8, a positional candidate for blood pressure and renal regulation: resequencing, association and in silico study.". BMC Med. Genet. 9: 25. 2008. doi:10.1186/1471-2350-9-25. PMID 18402670.
- "[Agenesis and aplasia of the kidney in children in the x-ray diagnostic picture].". Cesk Pediatr 30 (3): 94–7. 1975. PMID 1139715.
- "New loci associated with kidney function and chronic kidney disease.". Nat. Genet. 42 (5): 376–84. 2010. doi:10.1038/ng.568. PMID 20383146.
- "Genetic loci influencing kidney function and chronic kidney disease.". Nat. Genet. 42 (5): 373–5. 2010. doi:10.1038/ng.566. PMID 20383145.
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