Biology:Nickel-transporting ATPase

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Short description: Class of enzymes


nickel-transporting ATPase
Identifiers
EC number3.6.3.24
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a nickel-transporting ATPase (EC 3.6.3.24) is an enzyme that catalyzes the chemical reaction

ATP + H2O + Ni2+out [math]\displaystyle{ \rightleftharpoons }[/math] ADP + phosphate + Ni2+in

The 3 substrates of this enzyme are ATP, H2O, and Ni2+, whereas its 3 products are ADP, phosphate, and Ni2+.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (nickel-importing).

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1ZLQ and 2NOO.

References