Biology:Nucleoporin 205
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Nucleoporin 205 (Nup205) is a protein that in humans is encoded by the NUP205 gene.[1][2][3]
Function
Transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPC's are composed of subcomplexes, and NUP205 is part of one such subcomplex.[1] It has also been recently shown that Nup205 is required for proper viral gene expression.[4]
References
- ↑ 1.0 1.1 "Entrez Gene: NUP205 nucleoporin 205kDa". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23165.
- ↑ "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. October 1996. doi:10.1093/dnares/3.5.321. PMID 9039502.
- ↑ "Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assembly". Mol. Biol. Cell 8 (10): 2017–38. October 1997. doi:10.1091/mbc.8.10.2017. PMID 9348540. PMC 25664. http://www.molbiolcell.org/cgi/content/abstract/8/10/2017.
- ↑ "Interaction of adenovirus type 5 E4orf4 with the nuclear pore subunit Nup205 is required for proper viral gene expression". J Virol 88 (22): 13249–59. Nov 2014. doi:10.1128/JVI.00933-14. PMID 25210169.
Further reading
- "Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complex". Mol. Biol. Cell 16 (5): 2382–94. 2005. doi:10.1091/mbc.E04-10-0857. PMID 15703211.
- "Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assembly". Mol. Biol. Cell 8 (10): 2017–38. 1997. doi:10.1091/mbc.8.10.2017. PMID 9348540.
- "Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1". J. Biol. Chem. 277 (47): 45091–8. 2002. doi:10.1074/jbc.M207439200. PMID 12228227.
- "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. 2006. doi:10.1101/gr.4039406. PMID 16344560.
- "Direct interaction with nup153 mediates binding of Tpr to the periphery of the nuclear pore complex". Mol. Biol. Cell 14 (5): 1923–40. 2003. doi:10.1091/mbc.E02-09-0620. PMID 12802065.
- "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. 1996. doi:10.1093/dnares/3.5.321. PMID 9039502.
- "Defining the human deubiquitinating enzyme interaction landscape". Cell 138 (2): 389–403. 2009. doi:10.1016/j.cell.2009.04.042. PMID 19615732.
- "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. 2007. doi:10.1038/msb4100134. PMID 17353931.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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