Biology:Nucleoporin 160

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Nucleoporin 160 (Nup160) is a protein that in humans is encoded by the NUP160 gene.

NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM]

Further reading

• "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.". DNA Res. 3 (1): 17–24. 1996. doi:10.1093/dnares/3.1.17. PMID 8724849. 
• "An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells.". J. Cell Biol. 154 (6): 1147–60. 2001. doi:10.1083/jcb.200101081. PMID 11564755. 
• "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039. 
• "The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis.". Mol. Biol. Cell 15 (7): 3333–44. 2005. doi:10.1091/mbc.E03-12-0878. PMID 15146057. 
• "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315–23. 2004. doi:10.1101/gr.2122004. PMID 15231747. 
• "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334. 
• "Phosphoproteome analysis of the human mitotic spindle.". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. 2006. doi:10.1073/pnas.0507066103. PMID 16565220. Bibcode: 2006PNAS..103.5391N. 
• "The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly.". Mol. Biol. Cell 17 (9): 3806–18. 2006. doi:10.1091/mbc.E05-11-1061. PMID 16807356. 
• "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
• "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. 2007. doi:10.1038/msb4100134. PMID 17353931. 
• "Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex.". Proc. Natl. Acad. Sci. U.S.A. 104 (10): 3811–6. 2007. doi:10.1073/pnas.0700058104. PMID 17360435. Bibcode: 2007PNAS..104.3811G. 
• "The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions.". EMBO J. 26 (7): 1853–64. 2007. doi:10.1038/sj.emboj.7601642. PMID 17363900. 

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Nuclear pore complex protein Nup160