Biology:Nucleoporin 35

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Nucleoporin 35 (Nup35) is a protein that in humans is encoded by the NUP35 gene.

Background

This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is part of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC.

Further reading

• "Early embryonic requirement for nucleoporin Nup35/NPP-19 in nuclear assembly.". Developmental Biology 327 (2): 399–409. 2009. doi:10.1016/j.ydbio.2008.12.024. PMID 19146848. 
• "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
• "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. 2006. doi:10.1038/nbt1240. PMID 16964243. 
• "The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells.". Mol. Cell 22 (1): 93–103. 2006. doi:10.1016/j.molcel.2006.02.015. PMID 16600873. 
• "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. 2005. doi:10.1038/nature03466. PMID 15815621. Bibcode: 2005Natur.434..724H. 
• "Vertebrate Nup53 Interacts with the Nuclear Lamina and Is Required for the Assembly of a Nup93-containing Complex". Mol. Biol. Cell 16 (5): 2382–94. 2005. doi:10.1091/mbc.E04-10-0857. PMID 15703211. 
• "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334. 
• "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• "Proteomic analysis of the mammalian nuclear pore complex". J. Cell Biol. 158 (5): 915–27. 2002. doi:10.1083/jcb.200206106. PMID 12196509. 

External links

• Overview of all the structural information available in the PDB for UniProt: Q8NFH5 (Human Nucleoporin NUP35) at the PDBe-KB.