Biology:Perakine reductase
From HandWiki
| Perakine reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.317 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Perakine reductase (EC 1.1.1.317) is an enzyme with systematic name raucaffrinoline:NADP+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction
- raucaffrinoline + NADP+ [math]\displaystyle{ \rightleftharpoons }[/math] perakine + NADPH + H+
The biosynthesis of raucaffrinoline from perakine is a side route of the ajmaline biosynthesis pathway.
References
- ↑ "Purification, cloning, functional expression and characterization of perakine reductase: the first example from the AKR enzyme family, extending the alkaloidal network of the plant Rauvolfia". Plant Molecular Biology 67 (5): 455–67. July 2008. doi:10.1007/s11103-008-9331-7. PMID 18409028.
- ↑ "Expression, purification, crystallization and preliminary X-ray analysis of perakine reductase, a new member of the aldo-keto reductase enzyme superfamily from higher plants". Acta Crystallographica Section F 62 (Pt 12): 1286–9. December 2006. doi:10.1107/S174430910605041X. PMID 17142919.
External links
- Perakine+reductase at the US National Library of Medicine Medical Subject Headings (MeSH)
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