Biology:Phloroisovalerophenone synthase
From HandWiki
phloroisovalerophenone synthase | |||||||||
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Identifiers | |||||||||
EC number | 2.3.1.156 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a phloroisovalerophenone synthase (EC 2.3.1.156) is an enzyme that catalyzes the chemical reaction
- isovaleryl-CoA + 3 malonyl-CoA [math]\displaystyle{ \rightleftharpoons }[/math] 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one
Thus, the two substrates of this enzyme are isovaleryl-CoA and malonyl-CoA, whereas its 3 products are CoASH, CO2, and 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is isovaleryl-CoA:malonyl-CoA acyltransferase. Other names in common use include valerophenone synthase, and 3-methyl-1-(trihydroxyphenyl)butan-1-one synthase.
References
- "Enzymes from the biosynthesis of hop alpha and beta acids". Proc. 26th Congr. Eur. Brew. Conv.: 215–221. 1997.
- "4-Hydroxy-2-pyrone formation by chalcone and stilbene synthase with nonphysiological substrates". Phytochemistry 49 (7): 1945–51. December 1998. doi:10.1016/S0031-9422(98)00346-X. PMID 9883590.
Original source: https://en.wikipedia.org/wiki/Phloroisovalerophenone synthase.
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