Biology:Propanediol-phosphate dehydrogenase

From HandWiki
propanediol-phosphate dehydrogenase
Identifiers
EC number1.1.1.7
CAS number9028-15-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a propanediol-phosphate dehydrogenase (EC 1.1.1.7) is an enzyme that catalyzes the chemical reaction

propane-1,2-diol 1-phosphate + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] hydroxyacetone phosphate + NADH + H+

Thus, the two substrates of this enzyme are propane-1,2-diol 1-phosphate and NAD+, whereas its 3 products are hydroxyacetone phosphate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is propane-1,2-diol-1-phosphate:NAD+ oxidoreductase. Other names in common use include PDP dehydrogenase, 1,2-propanediol-1-phosphate:NAD+ oxidoreductase, and propanediol phosphate dehydrogenase.

References

  • "The metabolism of acetol phosphate. II. 1,2-Propanediol-1-phosphate dehydrogenase". The Journal of Biological Chemistry 234 (7): 1641–6. July 1959. PMID 13672935. 

External links