Biology:SMC2
From HandWiki
 Generic protein structure example |
Structural maintenance of chromosomes protein 2 (SMC-2) also known as chromosome-associated protein E (CAP-E) is a protein that in humans is encoded by the SMC2 gene.[1][2]
SMC-2 is a subunit of condensin I and II, large protein complexes involved in chromosome condensation.
Interactions
SMC2 has been shown to interact with DNMT3B.[3]
References
- ↑ "Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics". Proceedings of the National Academy of Sciences of the United States of America 95 (22): 12906–11. Oct 1998. doi:10.1073/pnas.95.22.12906. PMID 9789013. Bibcode: 1998PNAS...9512906S.
- ↑ "Entrez Gene: SMC2 structural maintenance of chromosomes 2". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10592.
- ↑ "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery". Nucleic Acids Research 32 (9): 2716–29. 2004. doi:10.1093/nar/gkh589. PMID 15148359.
Further reading
- "Condensin mutations and abnormal chromosomal structures in pyothorax-associated lymphoma". Cancer Science 98 (7): 1041–7. Jul 2007. doi:10.1111/j.1349-7006.2007.00500.x. PMID 17488335.
- "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology 3 (1): 89. 2007. doi:10.1038/msb4100134. PMID 17353931.
- "Nucleolar proteome dynamics". Nature 433 (7021): 77–83. Jan 2005. doi:10.1038/nature03207. PMID 15635413. Bibcode: 2005Natur.433...77A.
- "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery". Nucleic Acids Research 32 (9): 2716–29. 2004. doi:10.1093/nar/gkh589. PMID 15148359.
- "In vitro and in vivo interactions of DNA ligase IV with a subunit of the condensin complex". Molecular Biology of the Cell 14 (2): 685–97. Feb 2003. doi:10.1091/mbc.E01-11-0117. PMID 12589063.
- "Chromosome condensation by a human condensin complex in Xenopus egg extracts". The Journal of Biological Chemistry 276 (8): 5417–20. Feb 2001. doi:10.1074/jbc.C000873200. PMID 11136719.
- "A human condensin complex containing hCAP-C-hCAP-E and CNAP1, a homolog of Xenopus XCAP-D2, colocalizes with phosphorylated histone H3 during the early stage of mitotic chromosome condensation". Molecular and Cellular Biology 20 (18): 6996–7006. Sep 2000. doi:10.1128/MCB.20.18.6996-7006.2000. PMID 10958694.
External links
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Structural maintenance of chromosomes protein 2
- PDBe-KB provides an overview of all the structure information available in the PDB for Mouse Structural maintenance of chromosomes protein 2
 |
