Biology:Shikimate O-hydroxycinnamoyltransferase

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shikimate O-hydroxycinnamoyltransferase
Identifiers
EC number2.3.1.133
CAS number73904-44-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a shikimate O-hydroxycinnamoyltransferase (EC 2.3.1.133) is an enzyme that catalyzes the chemical reaction

4-coumaroyl-CoA + shikimate [math]\displaystyle{ \rightleftharpoons }[/math] CoA + 4-coumaroylshikimate

Thus, the two substrates of this enzyme are 4-coumaroyl-CoA and shikimate, whereas its two products are CoA and 4-coumaroylshikimate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is 4-coumaroyl-CoA:shikimate O-(hydroxycinnamoyl)transferase. This enzyme is also called shikimate hydroxycinnamoyltransferase. This enzyme participates in phenylpropanoid biosynthesis.

References

  • "Enzymatic-synthesis of hydroxycinnamic acid-esters of sugar acids and hydroaromatic acids by protein preparations from rye (Secale cereale) primary leaves". J. Plant Physiol. 131: 61–73. 1987. 
  • "Partial purification and properties of p-hydroxycinnamoyl-CoA:shikimate-p-hydroxycinnamoyl transferase from higher plants". Phytochemistry 19 (8): 1625–1629. 1980. doi:10.1016/S0031-9422(00)83782-6.