Biology:Thebaine 6-O-demethylase
From HandWiki
| Thebaine 6-O-demethylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.14.11.31 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Thebaine 6-O-demethylase (EC 1.14.11.31, T6ODM) is an enzyme with systematic name thebaine,2-oxoglutarate:oxygen oxidoreductase (6-O-demethylating).[1] This enzyme catalyses the following chemical reaction
- thebaine + 2-oxoglutarate + O2 [math]\displaystyle{ \rightleftharpoons }[/math] neopinone + formaldehyde + succinate + CO2
Thebaine 6-O-demethylase contains Fe2+.
References
- ↑ "Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy". Nature Chemical Biology 6 (4): 273–5. April 2010. doi:10.1038/nchembio.317. PMID 20228795.
External links
- Thebaine+6-O-demethylase at the US National Library of Medicine Medical Subject Headings (MeSH)
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