Chemistry:Azepane

Azepane

Ball-and-stick model of the azepane molecule
Names
Preferred IUPAC name Azepane
Other names Hexahydroazepine Hexamethyleneimine Homopiperidine Perhydroazepine HMI azacycloheptane
Identifiers
CAS Number	111-49-9 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:32616 Y
ChEMBL	ChEMBL1375444 N
ChemSpider	7828 Y
PubChem CID	8119
UNII	CZD076G73R Y
InChI InChI=1S/C6H13N/c1-2-4-6-7-5-3-1/h7H,1-6H2 Y Key: ZSIQJIWKELUFRJ-UHFFFAOYSA-N Y InChI=1/C6H13N/c1-2-4-6-7-5-3-1/h7H,1-6H2 Key: ZSIQJIWKELUFRJ-UHFFFAOYAF
SMILES C1CCCNCC1
Properties
Chemical formula	C6H13N
Molar mass	99.177 g·mol−1
Appearance	colorless liquid
Density	0.88 g/cm3
Melting point	−37 °C (−35 °F; 236 K)
Boiling point	138 °C (280 °F; 411 K) (749 mmHg)
Hazards
Flash point	30 °C (86 °F; 303 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Tracking categories (test):

• PairSizeSet

Azepane is the organic compound with the formula (CH₂)₆NH. It is a colorless liquid. A cyclic secondary amine, it is a precursor to several drugs and pesticides. It is produced by partial hydrogenolysis of hexamethylene diamine.

Like many amines, it reacts with carbon dioxide.

Azepane-containing drugs

1. AK-1 [330461-64-8]
2. Amicibone
3. Bazedoxifene
4. Bacmecillinam (KW 1100)
5. Brazergoline
6. BRN 1322519 [4082-37-5]
7. Buzepide (Fenpipramide homolog).
8. Cetiedil
9. Gimantan
10. Glidazamide
11. Glisoxepide
12. Glypinamide
13. Hexacaine
14. Mecillinam
15. Molinate
16. MR-16728 (cetiedil analogue)
17. Nabazenil
18. PD-157667
19. PD-158143
20. PD-151307
21. Pincainide
22. Prozapine
23. Setastine
24. Tolazamide
25. UCL 1608 Fb: [371172-30-4] Oxalate Salt: [371172-31-5]

See also

• Azepine