Chemistry:Setastine
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Short description: Chemical compound
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| Formula | C22H28ClNO |
| Molar mass | 357.92 g·mol−1 |
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Setastine (Loderix) is an antihistamine used to treat allergies and rhinitis.[1][2]
Pharmacology
Pharmacodynamics
Setastine acts as a highly selective H1 receptor antagonist.[3] It has no anticholinergic, antiadrenergic, or antiserotonergic effects.
Pharmacokinetics
Setastine penetrates the blood-brain-barrier poorly so it is only mildly sedating compared to related molecules like diphenhydramine.[3]
See also
References
- ↑ "Loderix (setastine) tablets in the treatment of allergic rhinoconjunctivitis". Therapia Hungarica 39 (1): 22–24. 1991. PMID 1677500.
- ↑ "Results obtained with Loderix tablet in chronic rhinitis patients". Therapia Hungarica 37 (4): 202–204. 1989. PMID 2576575.
- ↑ 3.0 3.1 "Pharmacology of the new H1-receptor antagonist setastine hydrochloride". Arzneimittel-Forschung 40 (12): 1340–1345. December 1990. PMID 1982751.
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