Chemistry:Drometrizole trisiloxane
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| Names | |
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| Preferred IUPAC name
2-(2H-Benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]-1-disiloxanyl]propyl]phenol | |
| Systematic IUPAC name
2-(2H-1,2,3-Benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-(2,2,4,6,6-pentamethyl-3,5-dioxa-2,4,6-trisilaheptan-4-yl)propyl]phenol | |
| Other names
2-(1,2,3-Benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-(2,2,4,6,6-pentamethyl-3,5-dioxa-2,4,6-trisilaheptan-4-yl)propyl]phenol
Silatrizole | |
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3D model (JSmol)
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| Properties | |
| C24H39N3O3Si3 | |
| Molar mass | 501.849 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Tracking categories (test):
Drometrizole trisiloxane (INCI) is a lipophilic benzotriazole derivative marketed as Mexoryl XL by L'Oréal and is used in sunscreens to absorb UV radiation. It is a broad-spectrum UV absorber with two absorption peaks, one at 303 nm (UVB) and one at 344 nm (UVA). Drometrizole trisiloxane and ecamsule (Mexoryl SX) are often used together, because they show a synergistic effect in UV protection.[1]
Availability
Sunscreens with drometrizole trisiloxane are approved within the EU,[2] Canada,[3] Australia,[4] Japan,[5] and other countries, but not in the United States.
See also
- Ecamsule (Mexoryl SX) – A UV filter often used with drometrizole trisiloxane
References
- ↑ Moyal D. (October 2004). "Prevention of ultraviolet-induced skin pigmentation". Photodermatol Photoimmunol Photomed 20 (5): 243–7. doi:10.1111/j.1600-0781.2004.00111.x. PMID 15379874.
- ↑ COUNCIL DIRECTIVE of 27 July 1976 on the approximation of the laws of the Member States relating to cosmetic products
- ↑ Sunburn Protectants , Health Canada
- ↑ Australian Regulatory Guidelines for OTC Medicines - Chapter 10
- ↑ Forestier, S.; Ortiz, S; Jitsukawa Setsuko (2004). "Mexoryl XL: A new UV protective agent". Fragr J 32 (4): 59–64. http://sciencelinks.jp/j-east/article/200411/000020041104A0360702.php. Retrieved 2008-08-01.
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