Chemistry:Erythrose 4-phosphate

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Erythrose 4-phosphate
Erythrose 4-phosphate.svg
Erythrose 4-phosphate.png
Names
IUPAC name
(2R,3R)-2,3-dihydroxy-4-oxobutyl phosphate
Other names
E4P
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
MeSH erythrose+4-phosphate
UNII
Properties
C4H9O7P
Molar mass 200.084 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Erythrose 4-phosphate is a phosphate of the simple sugar erythrose. It is an intermediate in the pentose phosphate pathway and the Calvin cycle.[1]

In addition, it serves as a precursor in the biosynthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. It is used in the first step of the shikimate pathway. At this stage, phosphoenolpyruvate and erythrose-4-phosphate react to form 3-deoxy-D-arabinoheptulosonate-7-phosphate (DAHP), in a reaction catalyzed by the enzyme DAHP synthase.

Biosynthesis of DAHP from phosphoenolpyruvate and erythrose-4-phosphate

It also used in 3-hydroxy-1-aminoacetone phosphate biosynthesis, which is a precursor of vitamin B6 in DXP-dependent pathway. Erythrose-4-phosphate dehydrogenase is used to produce erythronate-4-phosphate.

References