Chemistry:FGI-103
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Short description: Chemical compound
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| Formula | C19H16N6O |
| Molar mass | 344.378 g·mol−1 |
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FGI-103 is an antiviral drug developed as a potential treatment for the filoviruses Ebola virus and Marburg virus. In tests on mice FGI-103 was effective against both Ebola and Marburg viruses when administered up to 48 hours after infection. The mechanism of action of FGI-103 has however not yet been established, as it was found not to be acting by any of the known mechanisms used by similar antiviral drugs.[1][2][3]
See also
References
- ↑ "Antiviral activity of a small-molecule inhibitor of filovirus infection". Antimicrobial Agents and Chemotherapy 54 (5): 2152–9. May 2010. doi:10.1128/AAC.01315-09. PMID 20211898.
- ↑ "Mouse models for filovirus infections". Viruses 4 (9): 1477–508. September 2012. doi:10.3390/v4091477. PMID 23170168.
- ↑ "Ebola virus (EBOV) infection: Therapeutic strategies". Biochemical Pharmacology 93 (1): 1–10. January 2015. doi:10.1016/j.bcp.2014.11.008. PMID 25481298.
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| Dianlovirus |
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