Chemistry:Zymosterone
Zymosterone is a synthetic anabolic steroid that has been studied for its potential use in veterinary medicine and as a growth promoter in livestock. The compound is structurally related to testosterone and is known for its strong anabolic effects with relatively low androgenic activity.[1][2][3]
Uses
Zymosterone, NADPH and H(+) react to produce zymosterol and NADP(+). This reaction takes place in the endoplasmic reticulum, catalyzed by HSD17B7.[4]
The conversion of zymosterone to zymosterol plays an important role in the synthesis of ergosterol, a crucial component for maintaining the structure and functionality of fungal cell membranes. Similar to how cholesterol functions in animal cells, ergosterol supports the membrane's stability and participates in multiple cellular activities.[5]
References
- ↑ "zymosterone". Sigma Aldrich. https://www.sigmaaldrich.com/RU/en/product/avanti/700079p?srsltid=AfmBOooRCwaUMlV_nRzbZNoZwxU45P-fmtFOHNjda_o6hDWBer_p-ytO.
- ↑ Hitzler, Pascal; Fernández, Miriam; Janowicz, Krzysztof; Zaveri, Amrapali; Gray, Alasdair J. G.; Lopez, Vanessa; Haller, Armin; Hammar, Karl (24 May 2019) (in en). The Semantic Web: 16th International Conference, ESWC 2019, Portorož, Slovenia, June 2–6, 2019, Proceedings. Springer. p. 151. ISBN 978-3-030-21348-0. https://books.google.com/books?id=PxaaDwAAQBAJ&dq=Zymosterone&pg=PA151. Retrieved 20 July 2025.
- ↑ Hill, R. A.; Makin, H. L. J.; Kirk, D. N.; Murphy, G. M. (23 May 1991) (in en). Dictionary of Steroids. CRC Press. p. 110. ISBN 978-0-412-27060-4. https://books.google.com/books?id=AI7EnUyeEtUC&dq=Zymosterone&pg=PA110. Retrieved 20 July 2025.
- ↑ "Reactome | Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol)". reactome.org. https://reactome.org/content/detail/R-HSA-194632.
- ↑ "Zymosterone | Dihydrofolate reductase (DHFR) | MedChemExpress". MedchemExpress.com. https://www.medchemexpress.com/zymosterone.html?srsltid=AfmBOopeLfsKpO2W4ZpIRf1NwGqDRrNXIDIasgQRF4CGZIquQnAgUN1W.
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