Medicine:DTaP-IPV vaccine

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Short description: Vaccine against diphtheria, tetanus, whooping cough and polio
DTaP-IPV vaccine
DPT-IPV-japan Quattro back.jpg
DPT-IPV vaccine in Japan
Combination of
DTaP vaccineVaccine
Inactivated poliovirus vaccineVaccine
Clinical data
Trade namesKinrix, Quadracel, Boostrix-IPV, Infanrix-IPV, others
Other namesdiphtheria, tetanus, pertussis (acellular, component) and poliomyelitis (inactivated) vaccine (adsorbed, reduced antigen(s) content)
AHFS/Drugs.comKinrix Quadracel
Pregnancy
category
  • AU: A
Routes of
administration
Intramuscular injection
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
CAS Number

DTaP-IPV vaccine is a combination vaccine whose full generic name is diphtheria and tetanus toxoids and acellular pertussis adsorbed and inactivated poliovirus vaccine (IPV).[1][2]

It is also known as DTaP/IPV, dTaP/IPV, DTPa-IPV, or DPT-IPV.[1] It protects against the infectious diseases diphtheria, tetanus, pertussis, and poliomyelitis.[1]

Branded formulations marketed in the USA are Kinrix from GlaxoSmithKline[3] and Quadracel from Sanofi Pasteur.[4]

Repevax is available in the UK.[5][6]

Within Japan, the formulation is called 四種混合(shishukongou - "mixture of 4"). Astellas markets it under the クアトロバック ('Quattro-back') formulation, while another is available from Mitsubishi Tanabe Pharma named テトラビック ('Tetrabic')[7].[8] A previous product by Takeda Pharmaceutical Company has been withdrawn by the company.[9]

References

  1. 1.0 1.1 1.2 "Diphtheria, Tetanus, Pertussis (Acellular, Component) And Poliomyelitis (Inactivated) Vaccine (Adsorbed)". Drugs.com. https://www.drugs.com/international/diphtheria-tetanus-pertussis-acellular-component-and-poliomyelitis-inactivated-vaccine-adsorbed.html. 
  2. "DTaP-IPV-HepB-Hib Vaccine (Hexyon®): An Updated Review of its Use in Primary and Booster Vaccination". Paediatric Drugs 21 (5): 397–408. October 2019. doi:10.1007/s40272-019-00353-7. PMID 31444785. 
  3. "Kinrix". US Food and Drug Administration. https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm172495.htm. 
  4. "Quadracel". US Food and Drug Administration. https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm439856.htm. 
  5. "Repevax, suspension for injection, in pre-filled syringe - Summary of Product Characteristics (SmPC) - (emc)". https://www.medicines.org.uk/emc/product/5580#gref. 
  6. "14. Vaccines". British National Formulary (BNF) (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 - March 2021. p. 1381. ISBN 978-0-85711-369-6. 
  7. "医療用医薬品 : テトラビック (テトラビック皮下注シリンジ)". https://www.kegg.jp/medicus-bin/japic_med?japic_code=00060717. 
  8. "医療用医薬品 : クアトロバック (クアトロバック皮下注シリンジ)". https://www.kegg.jp/medicus-bin/japic_med?japic_code=00060732. 
  9. "【武田薬品】4種混合ワクチンの開発中止‐ノロウイルスなどに資源投入|薬事日報ウェブサイト". https://www.yakuji.co.jp/entry41529.html.