Medicine:Functio laesa

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Short description: Loss of organ function

Functio laesa is a term used in medicine to refer to a loss of function[1][2] or a disturbance of function.[3]

It was identified as the fifth sign of acute inflammation by Galen, who added it to the four signs identified by Celsus (tumor, rubor, calor, and dolor).[4]

The attribution to Galen is disputed,[3] and has variously been attributed to Thomas Sydenham[5] and Rudolf Virchow.[6]

References

  1. "Dorlands Medical Dictionary:cardinal signs". http://www.mercksource.com/pp/us/cns/cns_hl_dorlands_split.jsp?pg=/ppdocs/us/common/dorlands/dorland/seven/000096919.htm. 
  2. "Definition: functio laesa from Online Medical Dictionary". http://cancerweb.ncl.ac.uk/cgi-bin/omd?functio+laesa. 
  3. 3.0 3.1 Rather LJ (March 1971). "Disturbance of function (functio laesa): The legendary fifth cardinal sign of inflammation, added by Galen to the four cardinal signs of Celsus". Bull N Y Acad Med 47 (3): 303–22. PMID 5276838. 
  4. Porth, Carol (2007). Essentials of pahtophysiology: concepts of altered health states. Hagerstown, MD: Lippincott Williams & Wilkins. pp. 270. ISBN 978-0-7817-7087-3. 
  5. Dormandy, Thomas (2006). The worst of evils: man's fight against pain. New Haven, Conn: Yale University Press. pp. 22. ISBN 0-300-11322-6. https://archive.org/details/worstofevilsmans00dorm/page/22. 
  6. David Lowell Strayer; Raphael Rubin (2007). Rubin's Pathology: Clinicopathologic Foundations of Medicine 5th Edition. Hagerstown, MD: Lippincott Williams & Wilkins. pp. 37. ISBN 978-0-7817-9516-6.