Organization:Bioinformatics Resource Centers
The Bioinformatics Resource Centers (BRCs) are a group of five Internet-based research centers established in 2004 and funded by NIAID (the National Institute of Allergy and Infectious Diseases.)[1] The BRCs were formed in response to the threats posed by emerging and re-emerging pathogens, particularly Centers for Disease Control and Prevention (CDC) Category A, B, and C pathogens,[2] and their potential use in bioterrorism. The intention of NIAID in funding these bioinformatics centers is to assist researchers involved in the experimental characterization of such pathogens and the formation of drugs, vaccines, or diagnostic tools to combat them. The main goals of the BRCs are as follows:
1) To create comprehensive databases of reliable, up-to-date bioinformatic data (genetic, proteomic, biochemical, or microbiological) related to the pathogens of interest;
2) To provide researchers with easy access to this data through Internet-based search and data retrieval user interfaces;
3) To provide researchers with relevant, state-of-the art computational tools for bioinformatic analysis of these data.
Currently there are two BRC contracts awarded, one for bacteria and viruses, and the other for vectors, Eukaryotic protozoan and fungal pathogens and host response to pathogen infections.
| Name | Acrono name | Contributing organization(s) | Organisms covered | Example organisms (CDC Category) |
|---|---|---|---|---|
| Eukaryotic Pathogen, Vector and Host Informatics Resources | VEuPathDB | University of Pennsylvania University of Notre Dame |
All relevant pathogenic protozoa, fungi, vectors of pathogens and selected host organisms. In addition, important non-pathogenic organisms are included for phylogenetic inferences. | Crithidia (Other) Cryptosporidium (B) |
| Bacterial and Viral Bioinformatics Resource Center | BV-BRC | J. Craig Venter Institute |
All pathogenic bacteria and viruses | Influenza Virus (flu) (C) Arenaviridae (A) |
See also
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases
- Bioinformatics
- Categories of biological agents
References
- ↑ Overview, Bioinformatics Resource Centers , National Institute of Allergy and Infectious Diseases (NIAID), January 10, 2008.
- ↑ CDC Bioterrorism Agents and Diseases (By Category) , Centers for Disease Control and Prevention (Department of Health and Human Services), accessed July 8, 2008.
External links
- NIAID home page
- Bioinformatics Resource Centers The NIAID page describing the goals and activities of the BRCs
- VEuPathDB Eukaryotic Pathogen, Vector and Host Informatics Resources
- BV-BRC Bacterial and Viral Bioinformatics Resource Center
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