Biology:Sn-glycerol-3-phosphate 2-alpha-galactosyltransferase

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Short description: Class of enzymes
sn-glycerol-3-phosphate 2-alpha-galactosyltransferase
Identifiers
EC number2.4.1.137
CAS number80747-34-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a sn-glycerol-3-phosphate 2-alpha-galactosyltransferase (EC 2.4.1.137) is an enzyme that catalyzes the chemical reaction

UDP-galactose + sn-glycerol 3-phosphate [math]\displaystyle{ \rightleftharpoons }[/math] UDP + 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate

Thus, the two substrates of this enzyme are UDP-galactose and sn-glycerol 3-phosphate, whereas its two products are UDP and 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase. Other names in common use include floridoside-phosphate synthase, UDP-galactose:sn-glycerol-3-phosphate-2-D-galactosyl transferase, FPS, UDP-galactose, sn-3-glycerol phosphate:1->2' galactosyltransferase, floridoside phosphate synthetase, and floridoside phosphate synthase.

References

  • "The purification and characterization of a phospholipase A2 activity from the 106,000 X g pellet (microsomal fraction) of bovine brain acting on phosphatidylinositol". Can. J. Biochem. 60 (2): 108–17. 1982. doi:10.1139/o82-015. PMID 7083039.