Biology:Atopobium
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| Genus: | Atopobium Collins and Wallbanks 1993
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| Atopobium minutum (Hauduroy et al. 1937) Collins & Wallbanks 1993
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Atopobium is a genus of Actinomycetota, in the family Coriobacteriaceae. Atopobium species are anaerobic, Gram-positive rod-shaped or elliptical bacteria found as single elements or in pairs or short chains.
Atopobium vaginae was discovered in 1999.[2] This is a facultative anaerobic bacteria, which form small colonies on blood agar at 37 °C is also positive for acid phosphatase. This species has now been reclassified into the genus Fannyhessea following phylogenetic studies.
Clinical significance
The genus Atopobium may be associated with bacterial vaginosis.[3][4][5]
The genus may play a role in the development of Colorectal cancer. While the genus has been reported as overrepresented in feces of patients,[6] A. minutum has conversely shown a mild apoptotic effect on cancer cells in vitro and has been suggested to be comparable to probiotic bacteria in regards to colorectal cancer.[7]
Phylogeny
The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN)[8] and National Center for Biotechnology Information (NCBI).[9]
| 16S rRNA based LTP_08_2023[10][11][12] and 120 marker proteins based GTDB 08-RS214[13][14][15] | |||||||||||||||
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See also
References
- ↑ LPSN lpsn.dsmz.de
- ↑ "Characterization of a novel Atopobium isolate from the human vagina: description of Atopobium vaginae sp. nov.". Int J Syst Bacteriol 49 (4): 1573–6. 1999. doi:10.1099/00207713-49-4-1573. PMID 10555338.
- ↑ "Cloning of 16S rRNA genes amplified from normal and disturbed vaginal microflora suggests a strong association between Atopobium vaginae, Gardnerella vaginalis and bacterial vaginosis.". BMC Microbiol. 4 (16): 1573–6. Apr 21, 2004. doi:10.1186/1471-2180-4-16. PMID 15102329.
- ↑ "Detection of Atopobium vaginae in postmenopausal women by cultivation-independent methods warrants further investigation.". J Clin Microbiol 42 (16): 1829–1831. Apr 21, 2004. doi:10.1128/jcm.42.4.1829-1831.2004. PMID 15071062.
- ↑ "A preliminary survey of Atopobium vaginae in women attending the Dunedin gynaecology out-patients clinic: is the contribution of the hard-to-culturemicrobiota overlooked in gynaecological disorders?". The Australian and New Zealand Journal of Obstetrics and Gynaecology 45 (5): 450–2. October 2005. doi:10.1111/j.1479-828X.2005.00456.x. PMID 16171487.
- ↑ Ahn, J.; Sinha, R.; Pei, Z.; Dominianni, C.; Wu, J.; Shi, J.; Goedert, J. J.; Hayes, R. B. et al. (18 December 2013). "Human Gut Microbiome and Risk for Colorectal Cancer". J Natl Cancer Inst 105 (24): 1907–1911. doi:10.1093/jnci/djt300. PMID 24316595.
- ↑ Altonsy, M.O.; Andrews, S.C.; Tuohy, K.M. (28 February 2010). "Differential induction of apoptosis in human colonic carcinoma cells (Caco-2) by Atopobium, and commensal, probiotic and enterophathogenic bacteria: mediation by the mitochondrial pathway". International Journal of Food Microbiology 137 (2–3): 190–203. doi:10.1016/j.ijfoodmicro.2009.11.015. PMID 20036023.
- ↑ "Atopobium". https://lpsn.dsmz.de/genus/Atopobium.
- ↑ Sayers. "Atopobium". National Center for Biotechnology Information (NCBI) taxonomy database. https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Undef&id=1380&lvl=3&keep=1&srchmode=1&unlock.
- ↑ "The LTP". https://imedea.uib-csic.es/mmg/ltp/#LTP.
- ↑ "LTP_all tree in newick format". https://imedea.uib-csic.es/mmg/ltp/wp-content/uploads/ltp/LTP_all_08_2023.ntree.
- ↑ "LTP_08_2023 Release Notes". https://imedea.uib-csic.es/mmg/ltp/wp-content/uploads/ltp/LTP_08_2023_release_notes.pdf.
- ↑ "GTDB release 08-RS214". https://gtdb.ecogenomic.org/about#4%7C.
- ↑ "bac120_r214.sp_label". https://data.gtdb.ecogenomic.org/releases/release214/214.0/auxillary_files/bac120_r214.sp_labels.tree.
- ↑ "Taxon History". https://gtdb.ecogenomic.org/taxon_history/.
External links
Wikidata ☰ Q3629016 entry
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