Biology:Anthocyanidin 3-O-glucosyltransferase
| anthocyanidin 3-O-glucosyltransferase | |||||||||
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| Identifiers | |||||||||
| EC number | 2.4.1.115 | ||||||||
| CAS number | 65607-32-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, an anthocyanidin 3-O-glucosyltransferase (EC 2.4.1.115) is an enzyme that catalyzes the chemical reaction
- UDP-D-glucose + an anthocyanidin [math]\displaystyle{ \rightleftharpoons }[/math] UDP + an anthocyanidin-3-O-beta-D-glucoside
Thus, the two substrates of this enzyme are UDP-D-glucose and anthocyanidin, whereas its two products are UDP and anthocyanidin-3-O-beta-D-glucoside.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-D-glucose:anthocyanidin 3-O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-anthocyanidin 3-O-glucosyltransferase, UDP-glucose:anthocyanidin/flavonol 3-O-glucosyltransferase, UDP-glucose:cyanidin-3-O-glucosyltransferase, UDP-glucose:anthocyanidin 3-O-D-glucosyltransferase, and 3-GT. This enzyme participates in flavonoid biosynthesis.
References
- "Identification and properties of UDP-glucose: cyanidin-3-O-glucosyltransferase isolated from petals of the red campion (Silene dioica)". Biochem. Genet. 16 (11–12): 1045–58. 1978. doi:10.1007/BF00484525. PMID 751640.
- "Cloning and characterization of Vitis vinifera UDP-glucose:flavonoid 3-O-glucosyltransferase, a homologue of the enzyme encoded by the maize Bronze-1 locus that may primarily serve to glucosylate anthocyanidins in vivo". J. Biol. Chem. 273 (15): 9224–33. 1998. doi:10.1074/jbc.273.15.9224. PMID 9535914.
- "Reaction mechanism from leucoanthocyanidin to anthocyanidin 3-glucoside, a key reaction for coloring in anthocyanin biosynthesis". J. Biol. Chem. 276 (28): 25797–803. 2001. doi:10.1074/jbc.M100744200. PMID 11316805.
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