Biology:Flavanone 7-O-beta-glucosyltransferase

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Short description: Class of enzymes
flavanone 7-O-beta-glucosyltransferase
Identifiers
EC number2.4.1.185
CAS number125752-73-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a flavanone 7-O-beta-glucosyltransferase (EC 2.4.1.185) is an enzyme that catalyzes the chemical reaction

UDP-glucose + a flavanone [math]\displaystyle{ \rightleftharpoons }[/math] UDP + a flavanone 7-O-beta-D-glucoside

Thus, the two substrates of this enzyme are UDP-glucose and flavanone, whereas its two products are UDP and flavanone 7-O-beta-D-glucoside.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:flavanone 7-O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-flavanone 7-O-glucosyltransferase, naringenin 7-O-glucosyltransferase, and hesperetin 7-O-glucosyl-transferase.

References

  • "Flavanone-specific 7-O-glucosyltransferase activity in Citrus paradisi seedlings: purification and characterization". Arch. Biochem. Biophys. 282 (1): 50–7. 1990. doi:10.1016/0003-9861(90)90085-D. PMID 2171434. 
  • McIntosh CA; Mansell RL (1990). "Biosynthesis of naringin in Citrus paradisi - UDP-glucosyl-transferase activity in grapefruit seedlings". Phytochemistry 29 (5): 1533–1538. doi:10.1016/0031-9422(90)80115-W.