Biology:N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase

From HandWiki
Revision as of 00:45, 16 February 2024 by Steve Marsio (talk | contribs) (change)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Short description: Class of enzymes
N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase
Identifiers
EC number2.4.1.188
CAS number118731-83-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase (EC 2.4.1.188) is an enzyme that catalyzes the chemical reaction

UDP-glucose + N-acetyl-D-glucosaminyldiphosphoundecaprenol [math]\displaystyle{ \rightleftharpoons }[/math] UDP + beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol

Thus, the two substrates of this enzyme are UDP-glucose and N-acetyl-D-glucosaminyldiphosphoundecaprenol, whereas its two products are UDP and beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase. Other names in common use include UDP-D-glucose:N-acetylglucosaminyl pyrophosphorylundecaprenol, glucosyltransferase, uridine, diphosphoglucose-acetylglucosaminylpyrophosphorylundecaprenol, and glucosyltransferase.

References

  • "Solubilization and properties of UDP-D-glucose:N-acetylglucosaminyl pyrophosphorylundecaprenol glucosyltransferase from Bacillus coagulans AHU 1366 membranes". J. Biochem. (Tokyo) 104 (6): 985–8. December 1988. PMID 2977388.