Biology:2-Deoxystreptamine glucosyltransferase
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Short description: Class of enzymes
2-deoxystreptamine glucosyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.4.1.284 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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2-deoxystreptamine glucosyltransferase (EC 2.4.1.284, kanF (gene)) is an enzyme with systematic name UDP-alpha-D-glucose:2-deoxystreptamine 6-alpha-D-glucosyltransferase.[1] This enzyme catalyses the following chemical reaction
- UDP-alpha-D-glucose + 2-deoxystreptamine [math]\displaystyle{ \rightleftharpoons }[/math] UDP + 2'-deamino-2'-hydroxyparomamine
This enzyme is involved in the biosynthesis of kanamycin B and kanamycin C.
References
- ↑ "Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation". Nature Chemical Biology 7 (11): 843–52. October 2011. doi:10.1038/nchembio.671. PMID 21983602.
External links
- 2-deoxystreptamine+glucosyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
Original source: https://en.wikipedia.org/wiki/2-Deoxystreptamine glucosyltransferase.
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