Biology:2-coumarate O-beta-glucosyltransferase
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Short description: Class of enzymes
| 2-coumarate O-beta-glucosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.1.114 | ||||||||
| CAS number | 73665-97-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a 2-coumarate O-beta-glucosyltransferase (EC 2.4.1.114) is an enzyme that catalyzes the chemical reaction
- UDP-glucose + trans-2-hydroxycinnamate [math]\displaystyle{ \rightleftharpoons }[/math] UDP + trans-beta-D-glucosyl-2-hydroxycinnamate
Thus, the two substrates of this enzyme are UDP-glucose and trans-2-hydroxycinnamate, whereas its two products are UDP and trans-beta-D-glucosyl-2-hydroxycinnamate.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-o-coumarate glucosyltransferase, and UDPG:o-coumaric acid O-glucosyltransferase. This enzyme participates in phenylpropanoid biosynthesis.
References
- "trans-o-Hydroxylcinnamic acid glucosylation in cell-free extracts of Melilotus alba". Phytochemistry 6 (10): 1313–1318. 1967. doi:10.1016/S0031-9422(00)82872-1. https://digitalcommons.unl.edu/agronomyfacpub/176.
- "Intracellular localization of two enzymes involved in coumarin biosynthesis in Melilotus alba". Plant Physiol. 65 (2): 171–175. 1980. doi:10.1104/pp.65.2.171. PMID 16661155.
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