Biology:3-oxoacyl-(acyl-carrier-protein) reductase (NADH)
From HandWiki
Short description: Class of enzymes
| 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.212 | ||||||||
| CAS number | 82047-86-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) (EC 1.1.1.212) is an enzyme that catalyzes the chemical reaction
- (3R)-3-hydroxyacyl-[acyl-carrier-protein] + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] 3-oxoacyl-[acyl-carrier-protein] + NADH + H+
Thus, the two substrates of this enzyme are (3R)-3-hydroxyacyl-[acyl-carrier-protein] and NAD+, whereas its 3 products are 3-oxoacyl-[acyl-carrier-protein], NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (3R)-3-hydroxyacyl-[acyl-carrier-protein]:NAD+ oxidoreductase. Other names in common use include 3-oxoacyl-[acyl carrier protein] (reduced nicotinamide adenine, dinucleotide) reductase, and 3-oxoacyl-[acyl-carrier-protein] reductase (NADH).
References
- "The characteristics of some components of the fatty acid synthetase system in the plastids from the mesocarp of avocado (Persea americana) fruit". Eur. J. Biochem. 123 (3): 553–61. 1982. doi:10.1111/j.1432-1033.1982.tb06568.x. PMID 7075600.
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