Biology:7-deoxyloganin 7-hydroxylase
From HandWiki
Short description: Class of enzymes
7-deoxyloganin 7-hydroxylase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC number | 1.14.13.74 | ||||||||
CAS number | 335305-40-3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
|
In enzymology, a 7-deoxyloganin 7-hydroxylase (EC 1.14.13.74) is an enzyme that catalyzes the chemical reaction
- 7-deoxyloganin + NADPH + H+ + O2 [math]\displaystyle{ \rightleftharpoons }[/math] loganin + NADP+ + H2O
The 4 substrates of this enzyme are 7-deoxyloganin, NADPH, H+, and O2, whereas its 3 products are loganin, NADP+, and H2O.
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is 7-deoxyloganin,NADPH:oxygen oxidoreductase (7alpha-hydroxylating). This enzyme participates in indole and ipecac alkaloid biosynthesis.
References
- "7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures". Phytochemistry 58 (1): 53–8. September 2001. doi:10.1016/S0031-9422(01)00181-9. PMID 11524113.
![]() | Original source: https://en.wikipedia.org/wiki/7-deoxyloganin 7-hydroxylase.
Read more |