Biology:Acetoacetyl-CoA synthase
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Short description: Class of enzymes
Acetoacetyl-CoA synthase | |||||||||
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Identifiers | |||||||||
EC number | 2.3.1.194 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Acetoacetyl-CoA synthase (EC 2.3.1.194, NphT7) is an enzyme with systematic name acetyl-CoA:malonyl-CoA C-acetyltransferase (decarboxylating).[1] This enzyme catalyses the following chemical reaction
- acetyl-CoA + malonyl-CoA [math]\displaystyle{ \rightleftharpoons }[/math] acetoacetyl-CoA + CoA + CO2
The enzyme from the soil bacterium Streptomyces sp. CL190 produces acetoacetyl-CoA.
References
- ↑ "Unprecedented acetoacetyl-coenzyme A synthesizing enzyme of the thiolase superfamily involved in the mevalonate pathway". Proceedings of the National Academy of Sciences of the United States of America 107 (25): 11265–70. June 2010. doi:10.1073/pnas.1000532107. PMID 20534558.
External links
- Acetoacetyl-CoA+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
Original source: https://en.wikipedia.org/wiki/Acetoacetyl-CoA synthase.
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