Biology:Beta-mannosylphosphodecaprenol—mannooligosaccharide 6-mannosyltransferase

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Short description: Enzyme
Beta-mannosylphosphodecaprenol---mannooligosaccharide 6-mannosyltransferase
Identifiers
EC number2.4.1.199
CAS number125008-27-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Beta-mannosylphosphodecaprenol---mannooligosaccharide 6-mannosyltransferase (EC 2.4.1.199, mannosylphospholipid-methylmannoside alpha-1,6-mannosyltransferase, beta-D-mannosylphosphodecaprenol:1,6-alpha-D-mannosyloligosaccharide 1,6-alpha-D-mannosyltransferase) is an enzyme with systematic name beta-D-mannosylphosphodecaprenol:(1->6)-alpha-D-mannosyloligosaccharide 6-alpha-D-mannosyltransferase.[1] This enzyme catalyses the following chemical reaction

beta-D-mannosylphosphodecaprenol + (1->6)-alpha-D-mannosyloligosaccharide [math]\displaystyle{ \rightleftharpoons }[/math] decaprenol phosphate + (1->6)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-oligosaccharide

This enzyme is involved in the formation of mannooligosaccharides in the membrane of Mycobacterium smegmatis.

References

  1. "Synthesis of alpha 1----6-mannooligosaccharides in Mycobacterium smegmatis. Function of beta-mannosylphosphoryldecaprenol as the mannosyl donor". The Journal of Biological Chemistry 264 (36): 21621–8. December 1989. PMID 2480954. 

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